A CHANGE OF SCENERY
Credit: GAMES Magazine - Feb. 2001
Adam Fromm

What US city can become another US city if you change both of the A's in its name to E's? Both cities have five letters and both have the same first, third, and fourth letters.

HINTS:
#1: One city is east of the Mississippi River, and the other is west of it.
#2: The first letter in both names is T.

Answer:

The cities are TAMPA (Florida) and TEMPE (Arizona).