Ignoring spelling, each word and name in the clues below can be changed into a new word in the same way. What change has to be made, and what are the new words?

EGOTOTO
RENO
TEMPO
PSYCHO

Answer:

Replacing the final O in each name or word with either AL or LE creates a new word:

EGO - EAGLE
TOTO - TOTAL
RENO - RENAL
TEMPO - TEMPLE
PSYCHO - CYCLE

Credit: NY Times Crossword
August 19, 2012
Freddie Cheng
"OH, REALLY?"